SystemEU Valley - Open Call for Joint Interregional Projects

Funding cross-border consortia to develop, test and validate TRL 6–8 digital solutions for the healthcare, energy and mobility sectors.

TYPE OF PROJECTS TO BE FUNDED: Cross-border Joint Interregional Projects carrying out experimental development at TRL 6–8 to accelerate the digital transformation of healthcare, energy and mobility. Eligible activities include building system prototypes and pilot lines, testing under operational conditions, clinical studies, software-hardware integration and validation of certification dossiers, with projects expected to progress towards validated, market-ready solutions in real operational environments.

SECTORS / DOMAIN: Healthcare, including Digital Health and Medtech; Energy, including decentralised, clean and smart energy networks; and Mobility, including intelligent transport systems and logistics.

INDIVIDUAL OR CONSORTIUM: Consortium applications are mandatory. Small Projects require 2–3 independent legal entities from at least 2 SYSTEMEU regions and must include at least 1 startup or SME. Medium Projects require 3–5 independent legal entities from at least 3 SYSTEMEU regions and must include at least 1 research and knowledge dissemination organisation and 1 for-profit company. Flagship Projects require 5–8 independent legal entities covering all 5 SYSTEMEU regions and must include at least 1 research organisation, 1 company and 1 public authority or public-sector entity.

SPECIFIC ELIGIBILITY REQUIREMENTS: Applicants must be legal entities established in Bavaria (Germany), Norte Region (Portugal), Castile-León (Spain), Romania or Tuzla Canton (Bosnia and Herzegovina). Eligible entities include universities and Research and Technology Organisations, startups, SMEs, large enterprises, public authorities, hospitals and NGOs. Partners within a consortium must be legally independent. The project coordinator must be a startup, SME, university/RTO or NGO established in an eligible SYSTEMEU funding region. Applications must be submitted in English and comply with the applicable exclusion, sanctions, conflict-of-interest and supporting-document requirements.

SPECIFIC TOPICS OR CHALLENGES: Projects must address the digital transformation of one of three sectors: Healthcare, focusing on digital health, Medtech, clinical workflows, medical services and diagnostic pathways; Energy, focusing on digital innovations for decentralised, clean, secure and resilient energy systems; or Mobility, focusing on the digitisation of transport operations, public transit, autonomous systems and supply-chain logistics.

PROJECTS DURATION: 15–18 months.

BUDGET, FUNDING RATES AND PAYMENT CONDITIONS:
Funding rate: Startups may receive up to 100% funding, except startups based in Castile-León, where the rate is capped at 70%; SMEs may receive up to 70%; large enterprises up to 50%; universities and RTOs may receive up to 100% for non-economic activities; and public authorities and NGOs may receive up to 100% for eligible non-economic activities. The call overview also states that entities in Castile-León benefiting from an otherwise 100% rate are capped at 70%.
Budget conditions / limitations: The total call budget is €7,550,000. Maximum project budgets are €750,000 for Small Projects, €1,100,000 for Medium Projects and €2,200,000 for Flagship Projects. The minimum budget per partner is €50,000, while the cumulative FSTP support to any individual organisation across SYSTEMEU projects is capped at €600,000. At least 60% of the overall project budget must be allocated to startups, SMEs, public authorities/NGOs and/or universities/RTOs rather than large enterprises. Regional budget ceilings also apply.
Payments: Funding is provided as a performance-based lump sum in three tranches: 25% pre-financing, paid within 30 days of the bilateral subgrantee agreement entering into force and submission of the Individual Follow-Up Plan; 50% as an interim payment following approval of the Technical Interim Report at Month 9 or 10; and 25% as a final payment following submission, presentation and formal approval of the final progress performance report.

Closes

16/11/2026

Max funding per project

2.200.000€

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